Oral GLP-1 pills
Rybelsus, oral Wegovy (FDA-approved Dec 2025) and Lilly's small-molecule Foundayo/orforglipron (FDA-approved Apr 2026).
3 leading companies in oral glp-1 pills, one segment of pharma: glp-1 & obesity drugs — Semaglutide, tirzepatide and the next wave: about $132B in 2025 GLP-1 sales, with generics now open in Canada
new market segment · researched 2026-11-14
GLP-1 diabetes drugsWeight-loss (obesity) injectablesOral GLP-1 pillsNext-generation obesity drugsGeneric semaglutideSupply chain, compounding & pharmacy
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Leading oral glp-1 pills companies
3 companies, with the scale each source states. Scale is the whole company's unless the row says otherwise.
| Company | Where | What they do | Scale |
|---|---|---|---|
| Eli Lilly and Company LLY ↗ | Indianapolis, United States since 1876 | Tirzepatide (Mounjaro, Zepbound), orforglipron pill (Foundayo) and retatrutide in Phase 3. Reached $1T market cap Nov 2025. | revenue: 65.179 USD billions (total company) (2025) ↗ |
| Novo Nordisk NOVO-B.CO / NVO ↗ | Bagsværd, Denmark since 1923 | Semaglutide (Ozempic, Wegovy, Rybelsus, oral Wegovy) and liraglutide. CagriSema and amycretin in development. | revenue: 309.1 DKK billions (total company) (2025) ↗ |
| Chugai Pharmaceutical 4519.T ↗ | Tokyo, Japan since 1925 | Discovered orforglipron and licensed it to Lilly in 2018 (now Foundayo). | — |
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The pharma: glp-1 & obesity drugs market
The whole market this segment sits in.
global revenue · world132
↗USD billions (GLP-1 therapies, all indications) · 2025
Growth, segments, risks and every company in pharma: glp-1 & obesity drugs →
Quick answers
- What are oral glp-1 pills?
- Rybelsus, oral Wegovy (FDA-approved Dec 2025) and Lilly's small-molecule Foundayo/orforglipron (FDA-approved Apr 2026). They are one segment of the pharma: glp-1 & obesity drugs market.
- Who are the leading oral glp-1 pills companies?
- Eli Lilly and Company (United States), Novo Nordisk (Denmark), Chugai Pharmaceutical (Japan).
- Which oral glp-1 pills companies are publicly traded?
- Eli Lilly and Company (LLY), Novo Nordisk (NOVO-B.CO / NVO), Chugai Pharmaceutical (4519.T).
- How big is the pharma: glp-1 & obesity drugs market?
- For the whole pharma: glp-1 & obesity drugs market, not this segment alone: global revenue (world) 132 USD billions (GLP-1 therapies, all indications), 2025 — Managed Healthcare Executive.